I think for running long distance, you just have to take your own time. It is easy to 'hit the wall' for beginners, just like in Nautilus' case. Of course training and conditioning to run that kind of distance matters a lot. One thing I didn't know is that you can run too low on sodium by 'water parading', but I guess it made sense. I wondered whether all the supposed 'heat stroke' cases during army actually has to do with 'too much water' instead of 'too little water.' Remember the times when you have to finish one full water bottle, and then some. The medical services in the army should have known better right?